Laura B. Harrington, PhD, MPH, is an epidemiologist with expertise in cardiovascular epidemiology, the epidemiology of aging, and women’s health. As an Associate Investigator at the Kaiser Permanente Washington Health Research Institute (KPWHRI), her work leverages pharmacologic, medical-record based, lifestyle-based, and sex-specific exposure data to better understand associations between modifiable risk factors and cardiovascular and aging-related outcomes. She has particular interest and expertise in risk factors for incident and recurrent venous thromboembolism, in cardiovascular associations with brain health, and in sex-specific risk factors (e.g. endogenous sex hormone levels, vasomotor symptoms, hormone therapy use, characteristics of the menopause transition). She leads studies set in Kaiser Permanente Washington-based populations and existing epidemiologic cohort studies including the Women’s Health Initiative (WHI), the Adult Change in Thought (ACT) study, the Cardiovascular Health Study (CHS), the Nurses’ Health Studies (NHS) I and II, the Health Professionals Follow-up Study, and the Heart and Vascular Health (HVH) case-control study. Dr. Harrington is actively leading a new National Heart, Lung, and Blood Institute-funded inception cohort study of venous thromboembolism sequelae, the After Venous Thromboembolism Research (AFTER) Study.
Prior to joining KPWHRI in 2018, Dr. Harrington completed a postdoctoral fellowship at the Harvard T.H. Chan School of Public Health, earned her PhD in Epidemiology from the University of Washington, and her MPH in Epidemiology from the University of Michigan.
In addition to her role at KPWHRI, Dr. Harrington enjoys mentoring students and guest lecturing in her roles as Affiliate Assistant Professor of Epidemiology at the University of Washington School of Public Health and Assistant Professor of Health Systems Science at the Kaiser Permanente Bernard J. Tyson School of Medicine.
Venous thromboembolism; lifestyle-based risk factors (e.g., physical activity, sedentary behavior); pharmacologic risk factors; women’s cardiovascular health
Endogenous sex hormones; oral contraceptive and hormone therapy use; characteristics of the menopause transition; adverse pregnancy outcomes and long-term women’s health outcomes
Cardiovascular risk factors and events in relation to brain health
Comparative safety studies; pharmacoepidemiology; prescription use in relation to cardiovascular and aging-related outcomes; oral contraceptive and hormone therapy use
Hagan KA, Harrington LB, Kim J, Lindström S, Camargo CA Jr, Grodstein F, Kabrhel C. Adiposity throughout the life course and risk of venous thromboembolism. Thromb Res. 2018 Dec;172:67-73. doi: 10.1016/j.thromres.2018.10.024. Epub 2018 Oct 26. PubMed
Hagan KA, Harrington LB, Kim J, Zeleznik O, Rimm EB, Grodstein F, Kabrhel C. Reduction in physical function in women after venous thromboembolism. J Thromb Haemost. 2018 Jun 8. doi: 10.1111/jth.14196. [Epub ahead of print]. PubMed
Harrington LB, Hagan KA, Mukamal KJ, Kang JH, Kim J, Crous-Bou M, Lindström S, Rimm EB, Kabrhel C, Jensen MK. Alcohol consumption and the risk of incident pulmonary embolism in US women and men. J Thromb Haemost. 2018 Jul 5. doi: 10.1111/jth.14224. [Epub ahead of print]. PubMed
Kim J, Kraft P, Hagan KA, Harrington LB, Lindstroem S, Kabrhel C. Interaction of a genetic risk score with physical activity, physical inactivity, and body mass index in relation to venous thromboembolism risk. Genet Epidemiol. 2018 Jun;42(4):354-365. doi: 10.1002/gepi.22118. Epub 2018 Mar 8. PubMed
Harrington LB, Blondon M, Cushman M, Kaunitz AM, Allison MA, Wang L, Sullivan S, Woods NF, LaCroix AZ, Heckbert SR, McKnight B, Rossouw J, Smith NL. Vasomotor symptoms and the risk of incident venous thrombosis in postmenopausal women. J Thromb Haemost. 2018 May;16(5):886-892. doi: 10.1111/jth.13993. Epub 2018 Apr 2. PubMed
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Epidemiologist Laura B. Harrington, PhD, MPH, speaks about working in cardiovascular and aging research.